Permanent embryo arrest: molecular and cellular concepts

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Permanent embryo arrest: molecular and cellular concepts

Developmental arrest is one of the mechanisms responsible for the elevated levels of embryo demise during the first week of in vitro development. Approximately 10-15% of IVF embryos permanently arrest in mitosis at the 2- to 4-cell cleavage stage showing no indication of apoptosis. Reactive oxygen species (ROS) are implicated in this process and must be controlled in order to optimize embryo pr...

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ژورنال

عنوان ژورنال: Molecular Human Reproduction

سال: 2008

ISSN: 1360-9947,1460-2407

DOI: 10.1093/molehr/gan035